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J Nat Prod ; 65(9): 1377-9, 2002 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-12350172

RESUMO

Several quinone type compounds were isolated from the hexane, dichloromethane, and ethyl acetate extracts of the roots of Pentas longiflora. The hexane extract afforded two new compounds, [(3alpha,3'alpha,4beta,4'beta)-3,3']-dimethoxy-cis-[4,4'-bis(3,4,5,10-tetrahydro-1H-naphtho[2,3-c]pyran)]-5,5',10,10'-tetraone (1) and cis-3,4-dihydroxy-3,4-dihydromollugin (2), together with six known compounds, namely, pentalongin, mollugin, trans-3,4-dihydroxy-3,4-dihydromollugin, methyl-2,3-epoxy-3-prenyl-1,4-naphthoquinone-2-carboxylate, tectoquinone, and 3-hydroxymollugin. From the dichloromethane extract were isolated the three known compounds 3-methoxymollugin, methyl-3-prenyl-1,4-naphthoquinone-2-carboxylate, and scopoletin, while the ethyl acetate extract afforded the known 2-methoxy-3-methylanthraquinone.


Assuntos
Naftoquinonas/isolamento & purificação , Plantas Medicinais/química , Piranos/isolamento & purificação , Rubiaceae/química , Cromatografia em Camada Fina , Quênia , Espectrometria de Massas , Estrutura Molecular , Naftoquinonas/química , Naftoquinonas/farmacologia , Ressonância Magnética Nuclear Biomolecular , Raízes de Plantas/química , Piranos/química , Piranos/farmacologia , Escopoletina/química , Escopoletina/isolamento & purificação , Estereoisomerismo
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